CLIC6 and cancer: A study of the clinical and pathological features of pan-cancer in the TCGA database showed that CLIC6 expression levels were elevated in patients with early-stage BRCA, KICH, KIRP, LUAD, and THCA and gradually decreased as the tumor progressed, suggesting that CLIC6 expression may have potential value in the early diagnosis of the aforementioned cancers (Supplementary Figures S2A-E).