Heatmap analyses revealed a positive correlation between CLIC6 mRNA expression levels and the scores for tumor stroma, immune proliferation, and tumor purity in 15 distinct cancer types (COAD, GBM, HNSC, KIRC, LGG, LIHC, LUSC, PAAD, PCPG, PRAD, READ, SARC, SKCM, UCEC, and UVM) and negatively correlated with THCA (P < 0.05; Figure 8D). This evidence concerns the gene CLIC6 and cancer.