CLIC6 is lowly expressed in BRCA, LGG, HNSC, STAD, LUSC, and PRAD, and low CLIC6 expression is a risk factor for poorer prognosis in BRCA, HNSC, LUSC, and PRAD patients; conversely, low CLIC6 expression predicts better outcomes in LGG and STAD patients. This evidence concerns the gene CLIC6 and gastric adenocarcinoma.