Those with local vaginal IL-10 ≤ 55.90 pg/ml (median) were 2.92 times more likely to progress to CIN compared to those with IL-10 >55.90 pg/ml (OR = 2.92,95% CI: 1.09,7.84)(Table 3). This evidence concerns the gene IL10 and cervical squamous intraepithelial neoplasia.