Strikingly, in plasma samples alone, the sensitivity for the detection of HG-mucin-producing neoplasms was 100% (95% CI: 61%–100%), the specificity 100% (95% CI: 78%–100%), the PPV 100% (95% CI: 61%–100%), and the NPV 100% (95% CI: 78%–100%). Here, MUC5AC is linked to neoplasm.