Even if we consider these two cases as false positive, SiMBiT reached a sensitivity of 100% (95% CI: 76%–100%) and specificity of 96% (95% CI: 86%–100%) for the detection of HG-mucin-producing neoplasms in cyst fluids (PPV: 85%; 95% CI: 55%–98%; NPV: 100%; 95% CI: 94%–100%). Here, MUC5AC is linked to neoplasm.