A notable finding was a correlation between C1orf198 expression and macrophage infiltration, particularly M2-type macrophages—critical mediators of tumor-promoting inflammation—though the magnitude of this association (M2 macrophages: R = 0.156, P < 0.001) indicates C1orf198 likely acts in concert with other factors to modulate immune infiltration. This evidence concerns the gene C1orf198 and neoplasm.