This MR study suggests that genetic variations in NCF1, ATRN, PIANP, CD48, GABARAPL2, MAP1LC3B, ARF3, KIR2DL5A, DLK1, COLEC12, GPI, SEMG2, and EIF4B are causally associated with postherpetic neuralgia (PHN). Here, GABARAPL2 is linked to postherpetic neuralgia.