MYCN and neuroblastoma: In order to identify the potential significance of the changes in sEVs-derived miRNAs, sEVs-enriched fractions in 24 plasma samples from patients with NB (9 patients with MYCN+ HR, 8 patients with MYCN− HR, and 7 patients with MYCN− IR or LR) and 10 HCs were all sequenced for miRNAs in the first step.