Likewise, it inducesthe antioxidant activity of endogenous enzymes and normalizes theirexpression by mRNA, inducing the expression of the pyruvate carboxylaseenzyme, CASP-3 by activating the MAPK pathway. This pathway is critical for regulating cell survival,stress responses, and insulin signaling in target tissues, contributingto improved glucose uptake and metabolic control. Because of this, Am administration protects from the deleteriouseffects of dysglycemia and dyslipidemia through its antioxidant, anti-inflammatory,and antiapoptotic activity. The gene discussed is CASP3; the disease is metabolic syndrome.