CD274 and neoplasm: However, on day 25, combination therapy with 8 Gy + anti-PD-L1 concurrent dosing resulted in a tumor volume of 43.1 ± 16.8 mm3 (P = 0.0044 versus CT-only control), whereas the 8 Gy + anti-PD-L1 sequential group showed tumor volumes of 53.4 ± 19.8 mm3 (P = 0.6628 versus CT-only control) (Fig. 6a).