LPA and atherosclerosis: Among individuals with a family history of ASCVD, Lp(a) was significantly associated with both premature (HR: 1.43 per 50 mg/dL increase; 95 % CI: 1.19–1.71, p < 0.0001) and non-premature ASCVD (HR: 1.35 per 50 mg/dL increase [1.22–1.50], p < 0.0001).