In contrast, among white individuals, the relationship between Lp(a) and ASCVD was more pronounced, with a 74 % increased risk of premature ASCVD per 50 mg/dL increase (HR: 1.74[1.33–2.27], p < 0.0001) and a 29 % increased risk of non-premature ASCVD (HR: 1.29; [1.14–1.46], p < 0.0001). Here, LPA is linked to atherosclerosis.