Moreover, co-culture of human umbilical cord blood stem cells (hUCBSCs) with CD133+ glioma cells results in the down-regulation of several EMT-related markers, including N-cadherin, β-catenin, vimentin, TWIST1, and SOX2, while up-regulating E-cadherin 125. The gene discussed is CDH1; the disease is central nervous system cancer.