GATA2 and hemophagocytic syndrome: For genetic etiologies, reduced-toxicity allogeneic hematopoietic cell transplantation (allo-HCT) can reconstitute normal hematopoiesis in GATA2 deficiency [75, 84], while combined immunosuppression and antiviral therapy controls hyperinflammation in GATA2-associated HLH [76].