Excess visceral adipose tissue, or abdominal obesity, is a significant risk factor for metabolic abnormalities such as hypoalphalipoproteinemia (HALP), hypertriglyceridemia (HTG), hypercholesterolemia (HCL), insulin resistance (IR), hyperglycemia (HGL), and elevated levels of liver enzymes, alanine aminotransferase (ALT), and aspartate aminotransferase (AST). The gene discussed is GPT; the disease is apolipoprotein A-I deficiency.