In addition, research conducted suggests that the presence of psychosis in BD patients may increase their risk for non-fatal myocardial infarction or stroke [14]. Furthermore, patients with longer duration of BD present with increased left ventricular mass index (LVMI), which has been shown to be associated with increased levels of inflammatory markers such as platelet-lymphocyte ratio (PLR), C-reactive protein (CRP), and serum triglycerides [18]. This evidence concerns the gene CRP and myocardial infarction.