Over and above the cytokines and chemokines, products arising during the exudative phase of ARDS from endothelial cell damage, alveolar cell damage, and vascular permeability can also act as biomarkers; angiopoietin-1/2, endothelin, surfactant proteins-B/D, Krebs von den Lungen-6 (KL-6), soluble receptor for advanced glycation end-products (sRAGE), lactate dehydrogenase (LDH), von Willebrand factor (vWF) are a few them [52]. The gene discussed is VWF; the disease is acute respiratory distress syndrome.