Diagnostic characteristics of TRALI include symptom onset within six hours of blood transfusion, oxygen saturation (SpO2) < 90% on room air or arterial partial pressure of oxygen (PaO2)/fraction of inspired oxygen (FiO2) < 300 mmHg on room air, chest X-ray exhibiting evidence of pulmonary edema, risk factors as mentioned above, and brain natriuretic peptide (BNP) < 250 pg/mL [7]. This evidence concerns the gene NPPB and pulmonary edema.