There was no observed effect on total cholesterol, HDL, or LDL; however, improvements were observed in triglycerides (from 1.3 to 1.2 mmol/L). No change was observed in glucose or insulin levels, but CRP improved from 8.5 mg/L to 5.6 mg/L. The study also demonstrated a modest improvement in weight loss in patients with PCOS who received intervention with exenatide, as well as improvements in serum markers involved in endothelial function, inflammation, and clot function. This evidence concerns the gene CRP and polycystic ovary syndrome.