INS and polycystic ovary syndrome: There was no observed effect on total cholesterol, HDL, or LDL; however, improvements were observed in triglycerides (from 1.3 to 1.2 mmol/L). No change was observed in glucose or insulin levels, but CRP improved from 8.5 mg/L to 5.6 mg/L. The study also demonstrated a modest improvement in weight loss in patients with PCOS who received intervention with exenatide, as well as improvements in serum markers involved in endothelial function, inflammation, and clot function