CD8A and neoplasm: In this study, a unique intratumoral bacterial composition characterized by Pseudoxanthomonas, Streptomyces, Saccharopolyspora, and Bacillus clausii was identified as a highly predictive marker of long-term survival; these specific genera in the tumor were correlated with CD8 positive (CD8+) T cell tissue densities, suggesting that bacteria might contribute to the antitumor immune response by enhancing the requirement and activation of CD8+ T cells.