AFP and neoplasm: A breakdown of demographic and baseline factors isolating the post-LDT AFP-L3+/DCP+-containing phenotypes from the triple negative/AFP alone group revealed the more complex biomarker phenotypes contained a higher percentage of Child–Pugh B-C underlying disease (39–44% compared to 27%) and a larger median tumor size of 3.8 cm which contributed to an increase in BCLC-B staging due to multifocal disease (Supplemental Table 4).