BRD2 and polycystic ovary syndrome: Nonetheless, it appears contentious if various acupuncture protocols influence the monthly ovulation rate or LH/FSH levels in patients with PCOS.[57] However, the effects of different acupuncture protocols on ovulation rate and LH/FSH ratio in patients with PCOS remain controversial.[37,43] Nevertheless, recent meta-analyses have shown that acupuncture alone, as well as acupuncture combined with herbal medicine or moxibustion, has advantages in reducing serum LH/FSH levels in PCOS patients.[58]