A total of 66 direct or indirect comparisons were generated in the NMA, of which 7 comparisons were statistically significant, while the rest were not statistically significant, as shown in Figure 4B. The SUCRA results show that, in terms of ranking probability, RCGV has the highest cumulative probability (SUCRA: 76.6%), making it the best intervention to improve LH in patients with PCOS (Figure S1B, Supplemental Digital Content, https://links.lww.com/MD/Q404). The gene discussed is PLOD1; the disease is polycystic ovary syndrome.