IL1B and type 2 diabetes mellitus: A study conducted by Misaki et al in Japanese patients showed that circulating levels of IL-1β were positively correlated with FBS levels.[37] Fascinatingly, the mutant genotype of IL-1β SNP (rs16944) was also documented to be associated with an increase in the risk of glucose homeostasis in T2DM patients.[38] Another study showed a significant relationship between IL-1β rs16944 and elevation of FBS; this study does not agree with the current results.[27]