AHA is most commonly associated with underlying conditions such as autoimmune diseases, malignancies, pregnancy, or infections, though in many cases, no identifiable cause is found.[4,5] Among autoimmune conditions, bullous pemphigoid (BP), a chronic blistering skin disorder, has been reported in association with AHA, suggesting a possible immune-mediated link between the 2 diseases.[6,7] The exact mechanism remains unclear, but it is believed that immune dysregulation in BP may trigger the production of FVIII autoantibodies, leading to secondary AHA. Here, F8 is linked to autoimmune hemolytic anemia.