AHA is most commonly associated with underlying conditions such as autoimmune diseases, malignancies, pregnancy, or infections, though in many cases, no identifiable cause is found.[4,5] Among autoimmune conditions, bullous pemphigoid (BP), a chronic blistering skin disorder, has been reported in association with AHA, suggesting a possible immune-mediated link between the 2 diseases.[6,7] The exact mechanism remains unclear, but it is believed that immune dysregulation in BP may trigger the production of FVIII autoantibodies, leading to secondary AHA. The gene discussed is F8; the disease is autoimmune disease.