F8 and hemophilia: Acquired hemophilia A (AHA) is a rare but serious bleeding disorder caused by the development of autoantibodies against coagulation factor VIII (FVIII).[1] Unlike congenital hemophilia, which is linked to genetic mutations, AHA occurs in individuals with no prior bleeding history and typically presents with spontaneous or excessive bleeding in soft tissues, muscles, or mucous membranes.[2,3] The condition is often diagnosed when patients present with unexplained prolonged activated partial thromboplastin time (APTT) that does not correct with standard mixing studies.