Notably, among 213 ARID1A‐mutated and 575 CTNNB1‐mutated HCC patients, 79 (11%) exhibited co‐mutations (p < 0.01) (Figure 6B,C), while CTNNB1 mutations were mutually exclusive with TP53 mutations (n = 717) (Figure 6B). Here, CTNNB1 is linked to hepatocellular carcinoma.