Taken together, this study’s main findings demonstrate that combined aerobic and resistance ET can restore the protective anticontractile effect of tPVAT in HF post-MI by promoting adipocyte browning, improving the antioxidant and anti-inflammatory status, and enhancing the NE/β3-AR/adiponectin/AMPK/eNOS/NO pathway (Figure 6). The gene discussed is ADRB3; the disease is myocardial infarction.