Observing the mRNA expression levels of key pain-related MDGs in pancreatic tumor and normal samples, significant differences can be seen in the mRNA expression levels of PSMB8 and TRIP13 (PSMB8: Figure 4B, COL17A1: Figure 4D, BICC1: Figure 4F, CTRC: Figure 4H, TRIP13: Figure 4J). The gene discussed is CTRC; the disease is pancreatic neoplasm.