HLA-B and infection: For example, HLA-B Clade 1 has HLA-B and the primate orthologs like chimpanzee (Pan troglodytes) Patr-B, bonobo (Pan paniscus) Papa-B, Gorilla (Gorilla gorilla) Gogo-B, etc. In particular, -B Clade 1 contains the HLA-B*57:01 allele and the chimpanzee Patr-B*06:03 allele, both functionally associated with control of the progression of HIV-1 and SIVcpz infection, respectively [33]—yet, Papa-B Clade 1 alleles have not been identified in bonobos, despite that this clade is predicted to have been present in the common ancestor of chimpanzees and bonobos [31].