Furthermore, pharmacological inhibition of CXCR3 with AMG487, a CXCR3 antagonist, reduced migratory capacity of both T-ALL cell lines and primary cells to CXCL10 (Figure 3, D and E) but had no effect on T-ALL cell proliferation and viability (Supplemental Figure 3, D–F). The gene discussed is CXCL10; the disease is acute lymphoblastic leukemia.