the ablation of nigrostriatal DA neurons in DTA mice may besimilar to conditions of end stage PD; thus, motor impairments werenot improved by phasic activation of GHSRs expressed on nigrostriatal non-DA cells by a single ghrelin microinjection intothe SN. While the same dose of ghrelin improved the motor limitationsafter haloperidol treatment, which mimic an early stage PD. Here, GHRL is linked to Parkinson disease.