GHRL and anorexia nervosa: For example, Haruta et al. reported improved body weight andhypoglycaemia on a patient with severe anorexia nervosa followinga one-year intranasal dose of a ghrelin mimetic called growth hormonereleasing peptide-2 (GHRP-2). In a morerecent study, Poelman et al. showed that intranasally administeredGHRP-6 improved feeding on mice. Interestingly,this study found that no such effect was observed on the group givenintranasal ghrelin.