Figure 1 shows the Black-to-White PCa incidence RRs with 95% CIs for the same age groups in both pre-PSA and PSA eras, with fitted trend lines based on a weighted linear regression model. Table 1 presents the results of the weighted linear regression analysis and shows that incidence RRs decrease with age (slope = −0.116; 95% CI −0.183 to −0.049, P = .003) with each consecutive 5-year age group. There is no evidence that incidence RRs by age differed between the pre-PSA and PSA eras (P = .9). The gene discussed is KLK3; the disease is posterior cortical atrophy.