However, in NPDR, the levels of most inflammatory factors (IL-6, IL-8, MCP-1, VEGF, and IP-10) were significantly lower than those in our study; no significant correlation was observed between IL-6, IL-8, IP-10, MCP-1, or VEGF and glycemic parameters [37]. The gene discussed is CXCL8; the disease is non-proliferative diabetic retinopathy.