Although the gene signature of MEF2C-KO microglia does not exactly recapitulate a previously described state (that is, damage-associated microglia, proliferative region-associated microglia, lipid droplet-accumulating microglia and so on), there is overlap with multiple datasets, including the transcriptional and epigenetic signatures of ASD67, BD and SCZ30,53. This evidence concerns the gene MEF2C and Behcet disease.