IL6 and metabolic dysfunction-associated steatotic liver disease: Moreover, PS‐MPs have been shown to elevate pro‐inflammatory cytokines (e.g., Tumor Necrosis Factor‐α, TNF‐α; Interleukin‐6, IL‐6; Interleukin‐1β, IL‐1β) and activate inflammatory signaling pathways such as NF‐κB, thereby aggravating liver inflammation and potentially accelerating NAFLD progression.[10, 11, 12] Although MPs encompass a wide range of materials, including PS, polyethylene, polypropylene, and PET, most toxicological studies have focused on PS because of its availability and ease of use.