CYP2E1 and metabolic dysfunction-associated steatotic liver disease: Studies using human pluripotent stem cell‐derived liver organoids have further revealed that MPs upregulate hepatic HNF4A and CYP2E1, key regulators of lipid metabolism, insulin signaling, and mitochondrial function.[30] Our results similarly showed that prolonged MP ingestion results in more pronounced NAFLD‐like alterations in the liver tissues.