ACE and heart failure: The recommendation to use the angiotensin receptor–neprilysin inhibitor (ARNI) sacubitril/valsartan in patients with HFrEF15 who remain symptomatic on ACE inhibitors is based on the results of the PARADIGM‐HF (Prospective comparison of ARNI with ACE Inhibitor to Determine Impact on Global Mortality and morbidity in Heart Failure) study.81