Additionally, the combination of dysglycemia and HPV had a significant indirect effect on Ki-67 levels (estimate: 0.08, 95% CI: 0.06- 0.09, p<0.001).<h4>Conclusions</h4>Dysglycemia and HPV infection synergistically elevate cervical cancer risk, possibly influenced by Ki-67. Here, MKI67 is linked to cervical cancer.