EPHA1 and infection: In line with MHV68 gH/gL-Eph-interaction patterns observed in precipitation or ELISA, pre-incubation with soluble mEphA4 and mEphB3 reduced MHV68 infection of NIH 3T3 cells in a dose-dependent manner, while pre-treatment with mEphA2 and mEphA6 did not block infection (Fig 2C).