These included: olfactory transduction (rno04740), African trypanosomiasis (rno05143), renin secretion (rno04924), axon guidance (rno04360), cGMP–PKG signaling pathway (rno04022), vascular smooth muscle contraction (rno04270), platelet activation (rno04611), retrograde endocannabinoid signaling (rno04723), oxytocin signaling pathway (rno04921), and aldosterone synthesis and secretion (rno04925) (Supplementary Table S3). Here, REN is linked to human African trypanosomiasis.