RFWD3 and neoplasm: On the contrary, RFWD3 overexpression promoted tumor growth and increased tumor weight (Figure 4S,T), inhibited the tumor‐infiltrating CD8+ T cells, Granzyme B‐ and IFN‐γ‐expressing CD8+ T cells (Figure 4U–W), and decreased the number of tumor‐infiltrating NK cells and DCs (Figure 4X,Y), but increased the proportion of MDSCs (Figure 4Z).