RFWD3 and neoplasm: To determine whether the effects of RFWD3 on tumor growth are immune‐dependent or not, we subcutaneously inoculated shNC‐ or shRfwd3‐transfected LLC cells into NOD/ShiLtJGpt‐Prkdcem26Cd52Il2rgem26Cd22/Gpt (NSG) mice or Recombination‐Activating Gene 1 (Rag1) KO mice.