A previous study reported that chloroquine has been shown to enhance BMPR2 levels on the cell surface (Dunmore et al, 2013), whereas increased autophagic flux is associated with reduced BMPR2 levels in patients with pulmonary arterial hypertension (PAH) (Gomez-Puerto et al, 2019). This evidence concerns the gene BMPR2 and pulmonary arterial hypertension.