SIRT7 and central nervous system cancer: According to Fig. 1E and F, the statistical results of SIRT7 protein expression in normal brain tissues vs. gliomas tissues (F(3, 8) = 37.22, p < 0.0001) are presented below: normal brain tissues vs. WHO grade II glioma tissues: 0.57 ± 0.11 vs. 1.08 ± 0.16 (p = 0.0327), normal brain tissues vs. WHO grade III glioma tissues: 0.57 ± 0.11 vs. 1.76 ± 0.24 (p = 0.0002), normal brain tissues vs. WHO grade IV glioma tissues: 0.57 ± 0.11 vs. 2.11 ± 0.24 (p < 0.0001).