SIRT7 and central nervous system cancer: The statistical results of SIRT7 mRNA expression in normal brain tissues vs. gliomas tissues (F(3, 8) = 28.66, p = 0.0001) are presented below: normal brain tissues vs. WHO grade II glioma tissues: 1.00 ± 0.26 vs. 3.83 ± 0.30 (p = 0.0321), normal brain tissues vs. WHO grade III glioma tissues: 1.00 ± 0.26 vs. 5.67 ± 1.08 (p = 0.002), normal brain tissues vs. WHO grade IV glioma tissues: 1.00 ± 0.26 vs. 9.04 ± 1.85 (p < 0.0001).