Associations with complications, including delayed cerebral ischemia (DCI) and infection, were also assessed.<h4>Results</h4>CLDN3 and CLDN5 levels were significantly elevated in aSAH patients compared to controls (p <0.01 and p <0.0001, respectively), with CLDN5 levels consistently higher than CLDN3 at all time points (p <0.0001). The gene discussed is CLDN3; the disease is infection.