TSPO and Alzheimer disease: In AD, comparability across tracers was less robust, with [<sup>11</sup>C]PK11195 and [<sup>18</sup>F]GE-180 being most comparable, followed by [<sup>18</sup>F]GE-180 vs. [<sup>11</sup>C]PBR28, then by [<sup>11</sup>C]PK11195 vs. [<sup>11</sup>C]PBR28.<h4>Conclusion</h4>The pipeline was effective at harmonising TSPO-PET tracers and standardising the regional quantification of neuroinflammation in clinically matched cohorts of PSP, while the standardisation pipeline results were less robust across AD cohorts.