Some of these TFs (STAT5A, CREB3L1, ZNF24, HMGA1, IRF8, PAX8, CDX2, CREB3L2, TFEB, MGA, NFIB, KLF6, LEF1, HOXD13, HOXA13, HOXB13, GATA2) are known to be cancer drivers [85–88, 85–88]. This evidence concerns the gene IRF8 and cancer.