We next examined the expression of AMPs in flies after topical fungal infections for 48 and 72 h, and found that the antifungal Drosomycin (Drs) and Metchnikowin (Mtk) genes were significantly upregulated in flies infected with mutant strains, especially with ΔETS1.6 (p < 0.01) (Figure 2E,F). This evidence concerns the gene ADSL and fungal infectious disease.