C5orf24 and brain disorder: It has been reported that high‐fat models are often accompanied by neuronal apoptosis, and alterations in neuron‐microglia communication can lead to brain disorders, affecting synaptic function and neuronal survival.[47, 48] Microglia influence neurons through inflammatory responses and neurotrophic factors.[49] In the PA model, co‐culturing feimin‐specific microglia with neurons was associated with increased neuronal damage.