It has been shown to significantly lower blood glucose levels in mouse models of obesity and diabetes, demonstrating a particularly synergistic effect when combined with insulin.[23] In addition, recent research has shown that during exercise, cytoplasmic feimin in skeletal muscle interacts with FOXC2 during exercise, leading to the suppression of sarcolipin expression. This evidence concerns the gene C5orf24 and obesity due to melanocortin 4 receptor deficiency.