<h4>Abbreviations</h4>BMI, body mass index; CI, confidence interval; ESRD, end stage renal disease; HR, hazard ratio; IRB, Institutional Review Board; ICD, International Classification of Diseases; KTX, kidney transplantation; mTOR, mammalian target of rapamycin; PSM, propensity scoring matching; PTM: post-transplantation malignancy; SIR, standardized incidence ratio; SMR, standardized mortality rate.<h4>Objective</h4>Malignancy is a main cause of mortality and morbidity in kidney transplantation recipients. Here, MTOR is linked to stage 5 chronic kidney disease.