In a clinical study including of 30 patients with ALD, divided into four groups along clinical findings and liver histology, that are i), steatosis; ii), fibrosis; iii), hepatitis; and iv), cirrhosis, liver biopsies were tested for TGFB1, TGFB2, and TGFB3 gene expression by RT-PCR. Here, TGFB1 is linked to fibrosis.