ATP7B and neoplasm: As shown in the volcano plots in Fig. 3A, B, a total of 1002 proteins had a significant positive correlation with ATP7B and 502 proteins were significant negatively related in the normal tissues (Fig. 3A), and 171 proteins had a significant positive correlation and 54 proteins were significant negatively related in the tumor tissues (FDR < 0.05) (Fig. 3B).