PSP-PF exhibited higher total tau burdens in both cortical and subcortical regions, including the superior frontal cortex (7 [5, 9], P < 0.01), thalamic fasciculus (6 [5, 6], P < 0.01), red nucleus (10 [8, 11], P = 0.01), midbrain tectum (11 [9, 11], P = 0.03), pontine base (6 [5, 7], P = 0.01), and cerebellar white matter (4 [3, 6], P < 0.01). This evidence concerns the gene MAPT and pemphigus foliaceus.