Our experiment aligns with this observation, demonstrating that circ_0001239/YTHDC2-mediated KLF10 upregulation alleviates Spn-induced lung injury, whereas KLF10 downregulation diminishes the protective effect of METTL3 knockdown in neonatal mice with Spn-induced pneumonia. The gene discussed is YTHDC2; the disease is susceptibility to pneumonia measurement.