Von Willebrand factor (VWF), soluble P‐selectin, and D‐dimers are increased in COVID‐19 patients with more severe pulmonary disease (as measured by oxygen requirement), and these markers of coagulation correlate with markers such as monocyte chemotactic protein (MCP‐1)/C‐C motif ligand 2 (CCL2), tumor necrosis factor (TNF), CXCL10, and vascular cell adhesion molecule 1 and suggest both macrophage inflammatory response and EC activation.51 This evidence concerns the gene VWF and lung disorder.