Therefore, whereas the RAS is key to blood pressure control, the relative ratio of ACE/ACE2 is otherwise important, where high ACE/AngII drives pro‐inflammatory responses in the lung, high ACE2 reduces the pathology of ARDS and reciprocally, low ACE2 is likely an important contributor to inflammation in the COVID‐19 lung.9, 10, 11, 12, 13. Here, ACE is linked to acute respiratory distress syndrome.