In 5xFAD (6 months) and APP/PS1 (11 months) AD mouse models, transcranial 808 nm light treatment increased branch length and number, enlarged the diameter of MLVs, and enhanced the lymphangiogenesis as evidenced by increased LYVE-1 area in meninges(Wang et al. 2024). This evidence concerns the gene LYVE1 and Alzheimer disease.