RCAN1 and Alzheimer disease: Studies reported improvement in spatial learning and memory assessed by the MWM test in treatment groups receiving near-infrared light treatment, DSCR1 upregulation or crossing with DSCR1 mice, Yuanzhi powder (only with high-dose), donezepil, borneol and oxytocin, indicating enhanced cognitive performance in these AD models (Choi et al. 2021; J. Li et al. 2024a, b; Lin et al. 2021; Shan et al. 2024; Wang et al. 2024; Wu et al. 2023; C. Ye et al. 2024a, b).